菅 恵嗣 (助教)
菅 恵嗣 (すが けいし)
SUGA Keishi
[生年月日]
1985/10/6
経歴
奈良県出身。
2004. 3. 大阪明星高等学校卒業
2008. 3. 大阪大学基礎工学部化学応用科学科 卒業
2010. 3. 大阪大学大学院基礎工学研究科物質創成専攻 修士課程修了
2011. 4.-2013. 3. 日本学術振興会 特別研究員(DC2)
2013. 3. 大阪大学大学院基礎工学研究科物質創成専攻 博士課程修了
2013. 4. - 現在 大阪大学大学院基礎工学研究科物質創成専攻 助教
2015. 9. - 2015. 12. University of California, Davis, Researach Associate
原著論文 (Selected)
- Keishi Suga, Nozomi Watanabe, Hiroshi Umakoshi: Effect of Stearylguanidinium-Modified POPC Vesicles on the Melting Behaviour of tRNA Molecules. J. Phys. Chem. B, in press (2016)
- Tham Thi Bui, Keishi Suga, Hiroshi Umakoshi: Roles of Sterol Derivatives in Regulating the Properties of Phospholipid Bilayer Systems. Langmuir, 32 (24), 6176–6184 (2016)
- Keishi Suga, Kei Akizaki, Hiroshi Umakoshi: Quantitative Monitoring of Microphase Separation Behaviors in Cationic Liposomes Using HHC, DPH, and Laurdan: Estimation of the Local Electrostatic Potentials in Microdomains. Langmuir, 32, 3630–3636 (2016)
- Takaaki Ishigami, Atsushi Tauchi, Keishi Suga, Hiroshi Umakoshi: Effect of Boundary Edge of Heterogeneous Phase on Chiral Recognition Function of Ternary Liposomes. Langmuir, 32 (24), 6011–6019 (2016)
- Keishi Suga, Akari Hamasaki, Junpei Chinzaka, Hiroshi Umakoshi: Liposomes Modified with Cardiolipin Can Act as a Platform to Regulate the Potential Flux of NADP+-Dependent Isocitrate Dehydrogenase. Metabolic Eng. Commun., 3, 8-14 (2016)
- Keishi Suga, Seishiro Tanaka, Hiroshi Umakoshi: Magnesium Ion-Free Self-Cleavage of Hammerhead Ribozyme-Like RNA Assembly Induced by Liposome Binding. Eur. Biophys. J., 45(1), 55-62 (2016)
- Takaaki Ishigami, Keishi Suga, Hiroshi Umakoshi: Chiral Recognition of L-Amino Acid on Liposome Prepared by L-Phospholipid. ACS Appl. Mater. Interfaces, 7, 21065−21072 (2015)
- Hidemi Nakamura, Shogo Taguchi, Keishi Suga, Keita Hayashi, Ho-Sup Jung, Hiroshi Umakoshi: Characterization of Physicochemical Properties of Phospholipid Vesicles Prepared in CO2/Water Systems at High Pressure. Biointerphases, 10(3), Article ID 031005 (6 pages) (2015)
- Keita Hayashi, Madoka Kiriishi, Keishi Suga, Yukihiro Okamoto, Hiroshi Umakoshi: Investigation of Fatty Acid Ketohydrazone Modified Liposome’s Properties as a Drug Carrier. J. Drug Delivery, 2015, Article ID 481670 (7 pages) (2015)
- Keishi Suga, Tomohiro Yoshida, Haruyuki, Ishii, Yukihiro Okamoto, Daiusuke Nagao, Mikio Konno, Hiroshi Umakoshi: Membrane Surface-Enhanced Raman Spectroscopy (MSERS) for Sensitive Detection of Molecular Behaviour of Lipid Assemblies. Anal. Chem., in press (2015)
- Hye Sung Cho, Junsoo Kim, Keishi Suga, Takaaki Ishigami, Hyunchul Park, Jung Won Bang, Soonmin Seo, Mansoo Choi, Pahn-Shick Chang, Hiroshi Umakoshi, Ho-Sup Jung and Kahp-Yang Suh: Microfluidic Platforms with Monolithically Integrated Hierarchical Apertures for the Facile and Rapid Formation of Cargo-Carrying Vesicles. Lab on a Chip, 15, 373-377(2015)
- Keishi Suga, Tomoya Yokoi, Dai Kondo, Keita Hayashi, Seiichi Morita, Yukihiro Okamoto, Toshinori Shimanouchi, Hiroshi Umakoshi: Systematical Characterization of Phase Behaviors and Membrane Properties of Fatty Acid/Didecyldimethylammonium Bromide Vesicles. Langmuir, 30, 12721-12728 (2014)
- Hiroshi Umakoshi, Keishi Suga: Use Liposome as a Designable Platform for Molecular Recognition ~ from “Statistical Separation” to “Recognitive Separation” ~. Solvent Extr. Res. Dev., Jpn., 20, 1-13 (2013) [Review Article]
- Keishi Suga, Hiroshi Umakoshi: Detection of Nanosized Ordered Domains in DOPC/DPPC and DOPC/Ch Binary Lipid Mixture Systems of Large Unilamellar Vesicles Using a TEMPO Quenching Method. Langmuir, 29, 4830-4837 (2013)
- Keishi Suga, Tomoyuki Tanabe, Hiroshi Umakoshi: Heterogeneous Cationic Liposomes Modified with 3β-{N-[(N′,N′-Dimethylamino)ethyl]carbamoyl}cholesterol Can Induce Partial Conformational Changes in Messenger RNA and Regulate Translation in an Escherichia coli Cell-Free Translation System. Langmuir, 29, 1899-1907 (2013)
- Keishi Suga, Hibiki Tomita, Seishiro Tanaka, Hiroshi Umakoshi: Hydrophobic Properties of tRNA with Varied Conformations Evaluated by an Aqueous Two-Phase System. Int. J. Biol. Sci., 8, 1188-1196 (2012)
- Keishi Suga, Tomoyuki Tanabe, Hibiki Tomita, Toshinori Shimanouchi, Hiroshi Umakoshi: Conformational Change of Single-Stranded RNAs Induced by Liposome Binding. Nucleic Acids Res., 39, 8891-8900 (2011)
- Keishi Suga, Hiroshi Umakoshi, Hibiki Tomita, Tomoyuki Tanabe, Toshinori Shimanouchi, Ryoichi Kuboi: Liposomes Destabilize tRNA during Heat Stress. Biotechnol. J., 5, 526-529 (2010)
- Huong Thi Bui, Hiroshi Umakoshi, Keishi Suga, Masato Nishida, Toshinori Shimanouchi, Ryoichi Kuboi: Negatively-Charged Liposome is Potent Inhibitor of Protein Folding in Post-Translation Process of in vitro Gene Expression. Biochem. Eng. J., 46(2), 154-160 (2009)
- Hirhoshi Umakoshi, Keishi Suga, Huong Thi Bui, Masato Nishida, Toshinori Shimanouchi, Ryoichi Kuboi: Charged Liposome Affects the Translation and Folding Steps of in vitro Expression of Green Fluorescent Protein. J. Biosci. Bioeng., 108, 450-454 (2009)
著書・解説・総説
- 馬越 大, 島内 寿徳, 菅 恵嗣,
Membranomeを基盤とするBio-Inspired膜へのアプローチ,
膜, 37 (6), 264-269 (2012) - 菅 恵嗣,岡本 行広,馬越 大
リポソーム包埋ハイドロゲルの調製と応用
ゲルテクノロジーハンドブック(NTS出版),第4章(4), 674-681 (2014)
学会発表・講演
化学工学会年会・秋季大会
日本化学会
日本膜学会年会
分離技術会 他
受賞
- 日本学術振興会 特別研究員 (DC2) [2011-2013]
- 日本学術振興会 特別研究員 (PD) [2013-] (内定)
- GCOE Fellow 生命環境化学 (2010(A評価), 2011(A評価))
- 国内シンポジウム ポスター賞
(3件:日本膜学会、化学工学会バイオ部会、日本溶媒抽出学会) - 国際会議 ポスター賞
(3件:APBioChEC、JST-Symposium on Biomedicine, JSPS-SNSF Symposium on Membranome)
所属学会
- 化学工学会
- 日本化学会
- 日本膜学会
- 分離技術会
- 日本溶媒抽出学会
- 日本RNA学会
ひと言・モットー
全ての道はローマへ通ず。
得意技・趣味
Tuba一筋18年、好きですがなかなか上達しません…
市民奏楽団所属。